System and Method of Modeling the Pharmacodynamic Effect to Drugs Delivered to a Patient

A system for modeling the pharmacodynamic effect of anesthetic drugs delivered to a patient, the system comprising:

• an IV anesthetic drug delivery system attached to the patient for the delivery of a first anesthetic drug, the IV anesthetic drug delivery system including a monitor that measures a first anesthetic drug amount delivered to the patient;
• an anesthetic gas delivery system attached to the patient for the delivery of a second anesthetic drug to the patient, the anesthetic gas delivery system including a monitor that measures a second anesthetic drug amount delivered to the patient;
• a model database comprising a first drug interaction model and a second drug interaction model that models the pharmacodynamic effect experienced by the patient due to one or more anesthetic drugs;
• a drug interaction computer connected to the IV anesthetic drug delivery system to receive the first anesthetic drug amount, connected to the anesthetic gas delivery system to receive the second anesthetic drug amount, and connected to the model database to receive the first drug interaction model and the second drug interaction model, the drug interaction computer further receiving an additional anesthetic drug amount that is representative of an amount of an additional anesthetic drug delivered to the patient, the drug interaction computer being configured with computer readable code in order to apply the received first anesthetic drug and anesthetic gas amounts to the first drug interaction model to determine a first pharmacodynamic effect on the patient and to apply the received additional anesthetic drug amount to the second drug interaction model to determine a second pharmacodynamic effect on the patient;
• a rules database connected to the drug interaction computer and comprising a dominance rule, the drug interaction computer receiving the dominance rule from the rules database and using the dominance rule to compare the first pharmacodynamic effect and the second pharmacodynamic effect to determine a dominant interaction model;
• and
• a graphical display connected to the drug interaction computer that receives the determined dominant interaction model and presents the pharmacodynamic effect of the dominant interaction model.

A method of displaying a visual representation of the pharmacodynamic effect of anesthetic drugs delivered to a patient on a graphical display, the method comprising:

• obtaining from a patient a first anesthetic drug concentration, a second anesthetic drug concentration, and a third anesthetic drug concentration;
• applying the first anesthetic drug concentration and the second anesthetic drug concentration to a first pharmacodynamic model with a drug interaction computer to model a first pharmacodynamic effect attributable to the first anesthetic drug concentration and the second anesthetic drug concentration;
• applying the third anesthetic drug concentration to a second pharmacodynamic model with the drug interaction computer to model a second pharmacodynamic effect attributable to the third anesthetic drug concentration;
• determining, with the drug interaction computer, which of the first model and the second model is the dominant pharmacodynamic model by comparing the first pharmacodynamic effect and the second pharmacodynamic effect;
• and
• displaying the dominant pharmacodynamic model on the graphical display.