Brush CoPolymers
AssigneeBausch & Lomb Incorporated
InventorsDavid Paul Vanderbilt, Paul L. Valint, JR.
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Abstract
Brush copolymers containing (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units are disclosed.
Claims27
A brush copolymer comprising (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties;
- and (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units.
A biomedical device having a coating on a surface thereof, the coating comprising a brush copolymer comprising (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties and;
- (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units.
A packaging system for the storage of an ophthalmic device comprising a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising one or more brush copolymers comprising (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties;
- and (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units, wherein the solution has an osmolality of at least about 200 mOsm/kg, a pH of about 6 to about 9 and is heat sterilized.
Dependencies are inferred from the claim text.