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US 2010/0168725 A1Published application
Isotherm-based tissue ablation control system
AssigneeCryoMedix, LLC
InventorsAlexei Babkin, Peter Littrup
Life of this patent
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AssigneeCryoMedix, LLC
InventorsAlexei Babkin, Peter Littrup
Estimating the term…
A system and method for use with at least one cryoprobe for the treatment of biological tissue controls the energy applied to the tissue. The invention receives live procedure data such as temperature information from locations along the pathway of the cryogenic liquids, and calculates a procedure signature or profile based on the procedure data. In one embodiment, volumetric isotherms are calculated. The procedure signature is compared to a planning signature based on previously acquired image data and estimates of the thermal gradients from models. The system and method are further configured to automatically regulate the application of power based on analysis of the planning data to the procedure data.
A method of treatment of biological tissue using thermal tissue ablation, the method including treatment planning, monitoring and control by means of measuring and controlling of biological tissue response to thermal changes induced by probes inserted into the target treatment region, whereby said biological tissue response is measured and controlled in the temperature difference between the inlet temperature of circulating substances entering the exchange chamber of the ablation zone of the probe and the outlet temperature as it exits the chamber.
A protective device for preventing collateral tissue damage during a thermal ablation treatment of a target tissue, said ablation treatment comprising a treatment plan, and said protective device comprising diagnostic means for assessing the thermal response, or temperature difference, of the tissue the protective device is placed, and the protective device being linked to the treatment plan via thermal sensors to activate or shut off ablation treatment.
A multifunctional device for providing feedback to a controller comprising a fluid input line, and a fluid output line, and thermocouples on the input and output lines.
A controller comprising a processor operative to plan a treatment volume from previously acquired imaging data (with or without a clip, seed, or marker);
A system for use with at least one cryoprobe for the treatment of biological tissue with thermal ablation, said at least one cryoprobe comprising a distal treatment portion, an inflow conduit for transporting a cryogen towards said tissue treatment portion, and an outflow conduit for transporting said cryogen from said tissue treatment portion, the system comprising:
A method for treatment of a target volume of biological tissue using at least one thermal tissue ablation apparatus, said apparatus comprising a distal tissue treatment portion, an inlet conduit directing fluid towards said treatment portion, and an outlet conduit directing fluid from said treatment portion, and a fluid flowing through said inlet conduit and said outlet conduit, the method comprising:
A method for ablating a target tissue with cryo-energy arising from use of a cryogen circulating along a path, said method comprising the steps of:
Dependencies are inferred from the claim text.