US 2010/0168603 A1 · BRAIN STATE ANALYSIS BASED ON SELECT SEIZURE ONSET CHARACTERISTICS AND CLINICAL MANIFESTATIONS

Abstract

Systems and methods for developing a brain state analysis system using subject EEG data are provided. The analysis system distinguishes clinical from subclinical electrographic seizures and optionally distinguishes among different seizure onset characteristics. An algorithm trained on only clinical electrographic seizures may predict clinical seizures more accurately with fewer perceived false positives. In addition, algorithms trained on a particular onset condition may distinguish and advise on that onset condition when used by the patient.

Claims31

Dependent claims

A method of developing a brain state advisory system, comprising:

deriving a brain state advisory algorithm, the deriving step comprising:
analyzing patient EEG data,
identifying within the EEG data pro-ictal states correlated with clinical electrographic seizures, and
generating pro-ictal state alerts corresponding to pro-ictal states preferentially correlated with clinical electrographic seizures over pro-ictal states correlated with subclinical electrographic seizures;
and
placing the advisory algorithm in memory of the brain state advisory system.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application

12/646,783Filed 23 Dec 2009

Priority

23 Dec 2008

Published

1 Jul 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification8 codes

A61B 5/374
Analysis of electroencephalograms: detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
A61B 5/4094
Diagnosing or monitoring particular conditions of the nervous system: diagnosing or monitoring seizure diseases, e.g. epilepsy
A61B 5/6814
Specially adapted to be attached to a specific body part: head
A61B 5/6846
Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient: specially adapted to be brought in contact with an…

Brain state analysis based on select seizure onset characteristics and clinical manifestations

Life of this patent

Brain state analysis based on select seizure onset characteristics and clinical manifestations

Life of this patent

Abstract

Claims31