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US 2010/0168506 A1Published application
Method For Preparing Drug-Eluting Stent Having Nano-Structured Pattern
AssigneeKorea Institute of Science and Technology
InventorsMyoung-Woon Moon, Kwang Ryeol Lee, Dong Keun Han, Kwi- Deok Park
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Abstract
This invention relates to a method for preparing a drug-eluting stent using a chemical vapor deposition, the method comprising modifying the surface of a biodegradable polymer with nanostructures through a plasma-assisted chemical vapor deposition so as to improve drug-loading capability and drug elution rate.
Claims14
A method for preparing a drug-eluting stent, comprising the steps of:
- (a) forming a first biodegradable polymer layer on the surface of a stent;
- (b) forming a nanostructured pattern on the surface of the first biodegradable polymer layer by treatment with ion beams or plasma using a plasma-assisted chemical vapor deposition (PACVD);
- and, optionally,
- (c) forming a second biodegradable polymer layer on the first biodegradable polymer layer having the nanostructured pattern formed thereon,
- at least one of the first and second biodegradable polymer layers being loaded with identical or different drugs.
2 more elements
Dependencies are inferred from the claim text.