US 2010/0168457 A1 · MONOLITHIC ELECTROKINETIC PUMP FABRICATION

Abstract

High-pressure electrokinetic (“EK”) pumps comprising a hybrid monolith provide a high surface charge density and a continuous stable skeleton morphology with micrometer- sized through-pores. The hybrid monolith of the subject invention has superior mechanical strength and better stability in comparison to prior art monoliths with equivalent mechanical stability. The surface charge of the hybrid monolith can be modified and/or made stable by the use of different chemical reagents. The chemical reagents and resulting modification to the monolith serves to expand the usefulness of the hybrid monolith to a variety of pumping applications including chip-based systems and other applications where the ability to pump an acidic solution is required.

Claims15

Dependent claims

A hybrid monolith comprising a compound of the structural Formula I:

wherein:
X1, X2, and X3 vary independently and are selected from the group consisting of OH, alkoxy, alkyl and a bond bridged to the siloxane matrix;
X4 varies independently along the siloxane matrix as [—SiW1W2(CH2)mR2] and at least one substituent selected from the group consisting of H, alkyl, substituted alkyl, and a bond bridged to the siloxane matrix;
R1 is alkyl, alkenyl, either of which may be optionally substituted;
R2 is a primary, secondary, or tertiary amino group;
W1 and W2 vary independently and are selected from the group consisting of H, alkyl, alkoxy, substituted alkoxy, substituted alkyl, OH, and oxygen, wherein the oxygen is bridged to the siloxane matrix or [—SiW1W2(CH2)mR2];
m is an integer from 1-15;
n is an integer greater than 1;
and
the hybrid monolith having molecular weight between about 200 Da to about 100 kDa.

7 more elements

Dependencies are inferred from the claim text.

Monolithic electrokinetic pump fabrication

Life of this patent

Monolithic electrokinetic pump fabrication

Life of this patent

Abstract

Claims15