Chiral phosphorous compounds
AssigneeCeltic Catalysts Limited
InventorsDeclan Gilheany, Graham R. Cumming, Gary King, Matthias Voegler, Vladimir Larichev
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AssigneeCeltic Catalysts Limited
InventorsDeclan Gilheany, Graham R. Cumming, Gary King, Matthias Voegler, Vladimir Larichev
Estimating the term…
The present invention provides P-chiral compounds of general formulae (II) and (III): in formula (II) at least one of R21, R25, R26 and R30 is independently selected from CM alkyl, CF3, C1-4 alkoxy, phenyl and benzyloxy and the remaining substituents selected from R21, R25, R26 and R30 are hydrogen; at least one of R22, R24, R27 and R29 are independently selected from C1-14 alkyl, CF3, C1-14 alkoxy, phenyl and benzyloxy and the remaining substituents selected, from R22, R24, R27 and R29 are hydrogen; and R23 and R28 are independently selected from hydrogen, CM alkyl, CF3, C1-14 alkoxy, phenyl and benzyloxy; in formula (III) at least one of R21, R25, R26 and R30 is independently selected from phenyl and benzyloxy and the remaining substituents selected from R21, R25, R—26 and R30 are hydrogen; and R22, R—23 R24, R27, R28 and R29 are independently selected from hydrogen, C1-14 alkyl, CF3, C1-14 alkoxy, phenyl and benzyloxy.
A P-chiral compound of general formula (II):
A P-chiral compound of general formula (III):
A process for the preparation of a P-chiral compound of general formula (II) or general formula (III) which comprises reducing a P-chiral compound of formula (XII):
A process for the preparation of a P-chiral compound of general formula (II) or general formula (III) which comprises reducing a P-chiral compound of formula (XIII):
A process for the preparation of a P-chiral compound of general formula (II) or general formula (III) which comprises deboronating a P-chiral compound of formula (XIV):
Dependencies are inferred from the claim text.