A new peptide deformylase inhibitor compound and manufacturing process thereof

A compound of formula (I), all such racemic mixtures, optical isomers and diastereoisomers or a pharmaceutically acceptable salts thereof:

• wherein, A is selected from the group of consisting of —C(═O)NHOH or —N(CHO)OH;
• R1 represents hydrogen, C1-3 alkyl, C4-6 cycloalkyl, halogen or hydroxy group;
• R2 represents hydrogen, straight or branched C1-6 alkyl, straight or branched C2-6 alkenyl, C4-6 cycloalkyl, C4-6 heterocycle including nitrogen or oxygen, or benzyl group;
• R3 represents hydrogen, straight or branched C1-6 alkyl, straight or branched C2-6 alkenyl, C4-6 cycloalkyl, phenyl or benzyl group;
• X represents hydrogen or NR4R5;
• Each of R4 and R5 is independently hydrogen, straight or branched C1-3 alkyl, tert-butoxycarbonyl, benzyloxycarbonyl group;
• W represents carbon or nitrogen;
• Each of R6 and R7 is independently hydrogen, straight or branched C1-3 alkyl, tert-butoxylcarbonyl, benzyloxycarbonyl, 2,2,2-trichloroethoxycarbonyl or a group of formula (IIa), or (IIb), or (IIc):
• wherein, each of R8, R9, R10, R11 and R12 is independently hydrogen, straight or branched C1-3 alkyl, straight or branched C1-3 alkylamine, C3-6 cycloalkyl, C4-6 heterocycle, C1-3 alkoxyl, C1-3 acyl, C1-3 acyloxy, hydroxy, amido, halogen (fluoro, chloro, bromo and iodo), halogen-substituted C1-3 alkyl, cyano, nitro or morpholinyl group;
• Q represents carbon or nitrogen or oxygen;
• n is 0 or 1 or 2.