Prostaglandin pharmaceutical compositions

Compounds of general formula (I):

• A—Y—W (I)
• wherein
• A is a residue of prostaglandins or their derivatives of formula (II):
• B is —(CH2)m—CH3, m is 1-5;
• or
• V1 and V2, the same or different to each other, are zero or H;
• the bond is a single bond when V1 and/or V2 are H or a double bond;
• Y is zero;
• —(Cn′)alkyl-, ˜(Cn′)alkyl-CO—, ˜O—(Cn′)alkyl-O—, ˜OOC—(Cn′)alkyl-COO—;
• ˜O—(Cn′)alkyl-, ˜HN—(Cn′)alkyl-, ˜OOC—(Cn′)alkyl-;
• ˜(Cn′)alkyl-O—CO—(Cn″)alkyl-;
• ˜(Cn′)alkyl-CO—O—(Cn″)alkyl- wherein (Cn′)alkyl and (Cn″)alkyl are straight or branched, and n′ and n″, the same or different to each other, are 0-10;
• W is a polysulfurated group containing 2 or more atoms of sulphur, selected from the group comprising an organic thiosulfonate moiety or a dithiole-thione derivative, their stereoisomers and salts thereof.