Benzimidazole amido derivatives, their manufacture and use as pharmaceutical agents

A compound of formula I,

• wherein
• R1 is selected from the group consisting of:
• —R3, —O—R3 and —NR—R3;
• R2 is —X—R4;
• R3 is selected from the group consisting of:
• a) —(CH2)n—(O)m-phenyl, wherein the phenyl is optionally substituted one to three times with the substitutents being each independently selected from the group consisting of:
• alkyl, —O-alkyl, halogen, cyano, —N(alkyl)2, trifluoromethyl, and trifluoromethoxy;
• with the proviso that, if R1 is —O—R3 or —NR—R3 and n is 0, m is also 0.
• b) alkyl, wherein the alkyl is optionally substituted one to three times with the substituents being each independently selected from the group consisting of:
• —O-alkyl and halogen;
• c) alkenyl;
• d) heteroaryl;
• and
• e) (C3-C6) cycloalkyl;
• R4 is
• a) phenyl, wherein the phenyl is optionally substituted one to three times with the substitutents being each independently selected from the group consisting of:
• halogen, alkyl, —O-alkyl, —N(alkyl)2, trifluoromethyl and trifluoromethoxy;
• or
• b) pyridyl.
• X is (C1-C3)alkylene, wherein the alkylene is optionally substituted once or twice with the substitutents being each independently selected from the group consisting of:
• hydroxy, alkyl and halogen;
• R is hydrogen or (C1-C3)alkyl;
• m is 0 or 1;
• and
• n is 0, 1 or 2;
• or a pharmaceutically acceptable salt thereof.