Fused imidazole derivatives and use thereof as aldosterone synthase inhibitors

Compound of the general formula

• in which
• A is aryl or heterocyclyl;
• X is CR3R4 or, if Y is CR3R4, is alternatively a bond;
• Y is CR3R4, O, S(O)m or NR5;
• Z is CR3R4 or
• a) if Y is CR3R4, is alternatively O, S(O)m or NR5;
• or
• b) if Y is S(O)m, is alternatively NR5;
• or
• c) if Y is NR5, is alternatively S(O)m;
• R is C1-C8-alkoxy, C1-C8-alkyl, halogen, trifluoromethyl, tri-C1-C4-alkylsilyl, deuterium or hydrogen;
• R1 is C1-C8-alkoxy, C1-C8-alkoxycarbonyl, C1-C8-alkyl, mono- and di-C1-C8-alkylamino, mono- and di-C1-C8-alkylaminocarbonyl, C0-C8-alkylcarbonyl, amino, carbamoyl, carboxy-C1-C4-alkyl, carboxyl, cyano, halogen, oxo, trifluoromethyl, trifluoromethoxy, heterocyclyl or aryl, which radicals may be substituted by 1-4 C1 -C8-alkoxy, C1-C8-alkoxycarbonyl, C1-C8-alkyl, C0-C8-alkylcarbonyl, tri-C1-C4-alkylsilyl, C1-C8-alkylsulphonyl, aryl, cyano, halogen, heterocyclyl, oxo, trifluoromethyl or trifluoromethoxy;
• R2 a) is, independently of one another, C1-C8-alkyl, mono- and di-C1-C8-alkylamino, mono- and di-C1-C8-alkylaminocarbonyl, C0-C8-alkylcarbonyl, C1-C8-alkoxy, C1-C8-alkoxycarbonyl, amino, carbamoyl, carboxy-C1-C4-alkyl, carboxyl, cyano, halogen, oxo, trifluoromethyl, trifluoromethoxy, hydrogen, heterocyclyl or aryl, which radicals may be substituted by 1-4 C1-C8-alkoxy, C1-C8-alkoxycarbonyl, C1-C8-alkyl, C0-C8-alkylcarbonyl, tri-C1-C4-alkylsilyl, C1-C8-alkylsulphonyl, aryl, cyano, halogen, heterocyclyl, oxo, trifluoromethyl or trifluoromethoxy;
• or
• b) together with R1 is a fused-on 5-6-membered heterocyclic ring;
• R3 is hydrogen or C1-C8-alkyl;
• R4 a) is hydrogen or C1-C8-alkyl;
• or
• b) together with R3 is oxo;
• R5 is hydrogen, C1-C8-alkyl or C0-C8-alkylcarbonyl;
• m is a number 0, 1 or 2;
• n is a number 0, 1 or 2;
• p is a number 1 or 2;
• and its salts, preferably its pharmaceutically useful salts.