Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds
AssigneeAvon Products, Inc.
InventorsDmitri S. Ptchelintsev, Hong Hu, Gopinathan K. Menon, Kristine Schmalenberg, John W. Lyga
Life of this patent
Estimating the term…
Abstract
Cosmetic compositions comprising 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.
Claims20
A method for providing a benefit to human skin comprising topically applying to the skin of an individual in need thereof an effective amount of a 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamide or a cosmetically acceptable salt thereof in a cosmetically acceptable vehicle.
The method according to claim 11, wherein said skin benefit is selected from the group consisting of:
- (a) treatment, reduction, and/or prevention of fine lines or wrinkles,
- (b) reduction of skin pore size,
- (c) improvement in skin thickness, plumpness, and/or tautness;
- (d) improvement in skin suppleness and/or softness;
- (e) improvement in skin tone, radiance, and/or clarity;
- (f) improvement in procollagen and/or collagen production;
- (g) improvement in maintenance and remodeling of elastin;
- (h) improvement in skin texture and/or promotion of retexturization;
- (i) improvement in skin barrier repair and/or function;
- (j) improvement in appearance of skin contours;
- (k) restoration of skin luster and/or brightness;
- (l) replenishment of essential nutrients and/or constituents in the skin;
- (m) improvement of skin appearance decreased by menopause;
- (n) improvement in skin moisturization;
- (o) increase in skin elasticity and/or resiliency;
- or
- (p) treatment, reduction, and/or prevention of skin sagging.
A method for treating wrinkles and/or fine lines comprising topically applying to said wrinkle and/or fine line on the skin of an individual in need thereof an effective amount of a 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamide or a cosmetically acceptable salt thereof in a cosmetically acceptable vehicle for a time sufficient to reduce the severity of said wrinkles of fine lines.
A cosmetic composition comprising from about 0.0001% to about 25% by weight of a 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamide in a cosmetically acceptable vehicle.
Dependencies are inferred from the claim text.