Screening method
OwnerTakayuki Hida, Tomoko Sekiya +6inventors
InventorsTakayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Toru Arai
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OwnerTakayuki Hida, Tomoko Sekiya +6inventors
InventorsTakayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Toru Arai
Estimating the term…
The present inventors have found that relaxin-3 has a feeding-stimulating activity, a body weight increasing activity, and fat weight increasing activity by intracerebroventricularly administering relaxin-3 to rats and observing the amount of feeding, body weight and fat weight, and so on after the administration. According to the present invention, a polypeptide having useful effects in stimulating feeding, increasing body weight, and fattening; a therapeutic agent containing said polypeptide; a method of screening for a compound, a substance, or a salt thereof which activates or suppresses a receptor of said polypeptide; a kit for said screening; and an agent which comprises a substance which inhibits expression of said polypeptide, such as a feeding-surpressing agent, a therapeutic agent for the treatment of obesity, and a therapeutic agent for the treatment of diabetes.
1-52. (canceled)
A method of screening for a compound which stimulates feeding or a salt thereof, comprising the steps of
A method of screening for a compound which stimulates or suppresses feeding or a salt thereof, comprising the step of
A kit for screening for a compound which stimulates feeding or a salt thereof, comprising the steps of
A kit for screening for a compound which stimulates or suppresses feeding or a salt thereof, comprising the step of
A method of recovering feeding and/or body weight gain in a patient having a disease involving reduced feeding and/or weight loss, comprising administering an effective amount of relaxin-3, or a salt thereof, to a patient in need thereof.
A method of screening for a compound which increases body weight or a salt thereof, comprising the steps of
A method of screening for a compound which increases or decreases body weight or a salt thereof, comprising the step of
A kit for screening for a compound which increases body weight or a salt thereof, comprising the steps of
A kit for screening for a compound which increases or decreases body weight or a salt thereof, comprising the step of
A method of screening for a compound involved in the control of obesity or a salt thereof, comprising the steps of
A method of screening for a compound involved in the control of obesity or a salt thereof, comprising the step of
A kit for screening for a compound involved in the control of obesity or a salt thereof, comprising the steps of
A kit for screening for a compound involved in the control of obesity or a salt thereof, comprising the step of
Dependencies are inferred from the claim text.