Systems and Methods for Applying Cross-Linked Mechanical Barriers
AssigneeNeoMend, Inc.
InventorsGregory M. Cruise, Olexander Hnojewyj
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Abstract
A delivery device applies a biocompatible and biodegradable barrier material to a tissue region, e.g., to seal a vascular puncture site. The material comprises two liquid components, which are pre-packaged in individual dispensers. Upon mixing, the liquid components cross-link to create a barrier matrix. A holder attaches to the delivery device. The holder mutually supports the first and second dispensers while the protein solution and polymer solution are conveyed from the dispensers into a fluid delivery channel. The protein and polymer solutions mix as a result of flow through the channel.
Claims9
A biocompatible and biodegradable material applied to seal a vascular puncture comprising a mixture of protein solution and a polymer solution comprising poly(ethylene glycol)(PEG) with a functionality of at least three, wherein, upon mixing, the protein solution and the polymer solution cross link to form a solid matrix that seals the vascular puncture without use of a photo initiator and ultraviolet light energy.
Dependencies are inferred from the claim text.