Single Use Centrifuge System
AssigneePneumatic Scale Corporation
InventorStephen B. Kessler
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Abstract
An improved centrifuge system having a single means for both feeding and collecting liquid streams aseptically from rotating components is provided. Also methods and apparatus for centrifugal separation of cells from cell culture media of large cell culture batches by processing a large volume within a few hours, using pre-sterilized, single-use fluid path components. The apparatus uses a sealing approach that improves reliability while avoiding air contamination as well as shedding from mechanical seals. The risk of process liquid leaks is minimized.
Claims15
A single use centrifuge system for centrifugal separation of cells in a cell culture batch, wherein cell suspensions are processed at a flow rate of about 3 to about 30 liters per minute.
A single use centrifuge system for centrifugal separation of cells in a cell culture batch, wherein a flexible cylindrical liner is sealed to an upper element and the lower element by a combination of (i) thermal bonding and (ii) compression nubbins.
Dependencies are inferred from the claim text.