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AssigneeNational Food Research Institute
InventorsSachiko Machida, Kiyoshi Hayashi, Ken Tokuyasu, Yoshikiyo Sakakibara, Shigeru Matsunaga
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The present invention provides a method for detecting modified LDL, abnormal cells or bacteria using an intermolecular interaction analysis method, in which a region involved in ligand recognition by a receptor is expressed, without modification or as a biotinylated protein, in cells or in a test tube, and thereafter, the expressed region or the expressed biotinylated protein is immobilized via avidin or streptavidin to a solid phase while the orientation thereof is maintained, and the immobilized protein is utilized; and a kit for detecting the modified LDL or the like.
A receptor chip, on which a recombinantly expressed biotinylated receptor protein is immobilized via a factor capable of specifically binding to biotin.
A method for producing a receptor chip, comprising the steps of:
A method for producing a receptor chip, comprising the steps of:
Dependencies are inferred from the claim text.