Assessing risk of cardiac intervention in patients suffering from stable coronary heart disease based on gdf-15

Abstract

Described is a method for diagnosing whether a percutaneous cardiac intervention (PCI) in a subject suffering from a stable coronary heart disease was successful, the method comprising determining the amount of GDF-15 in a first sample of the subject which has been obtained after PCI and comparing the determined amount of GDF-15 with a reference amount of GDF-15 which is determined in a second sample of the subject suffering from a stable coronary heart disease obtained prior to PCI, whereby it is diagnosed whether PCI was successful. The invention also relates to the use of means for determining the amount of GDF-15 and, preferably, a natriuretic peptide and/or a cardiac troponin for the preparation of a diagnostic composition for diagnosing whether a PCI in a subject suffering from a stable coronary heart disease was successful.

Dependencies are inferred from the claim text.