Blood cell separation

A method of cultivating foetal cells, the method comprising:

• enriching cells having a different expression pattern of at least one foetal marker compared to the expression pattern of the marker in an equivalent maternal cell, the foetal marker being selected from the group consisting of:
• HSP-60, a monoamine oxidase, glutamine synthase, Ara-70, Ara-54, FLJ20202, DCN-I protein, RAB5A, HSP-7C, EF1A1, GRP78, MYL4, DnaJ homolog subfamily B member 14, Vinculin, Desmoplakin, AMMECR1-like protein, Extracellular matrix protein 2 precursor protein, uncharacterised 1 protein Cxorf57, Peroxiredoxin 1, and Peroxiredoxin 2.

(canceled)

A foetal cell isolation kit, comprising:

• means for detecting whether a cell has a different expression pattern of at least one foetal marker compared to the expression pattern of the marker in an equivalent maternal cell, and
• means of separating a cell having the different expression pattern of the at least one foetal marker from a cell which does not have the different expression pattern of the at least one foetal marker, wherein the foetal marker is selected from the group consisting of:
• HSP-60, a monoamine oxidase, glutamine synthase, Ara-70, Ara-54, FLJ20202, DCN-I protein, RAB5A, HSP-7C, EF1A1, GRP78, MYL4, DnaJ homolog subfamily B member 14, Vinculin, Desmoplakin, AMMECR1-like protein, Extracellular matrix protein 2 precursor protein, uncharacterised protein Cxorf57, Peroxiredoxin 1, and Peroxiredoxin 2.

(canceled)

(canceled)

An apparatus comprising:

• means for detecting whether a cell has a different expression pattern of at least one foetal marker compared to the expression pattern in a maternal cell, and
• means of separating a cell having the different expression pattern of the at least one foetal marker from a cell which does not have the different expression pattern of the at least one foetal marker, wherein the foetal marker is selected from the group consisting of:
• HSP-60, a monoamine oxidase, glutamine synthase, Ara-70, Ara-54, FLJ20202, DCN-I protein, RAB5A, HSP-7C, EF1A1, GRP78, MYL4, DnaJ homolog subfamily B member 14, Vinculin, Desmoplakin, AMMECR1-like protein, Extracellular matrix protein 2 precursor protein, uncharacterised protein Cxorf57, Peroxiredoxin 1, and Peroxiredoxin 2.

A method of determining that a cell is a foetal cell, the method comprising:

• detecting in the cell at least one foetal marker having a different expression pattern compared to the expression pattern in an equivalent maternal cell, wherein the foetal marker is selected from the group consisting of:
• HSP-60, a monoamine oxidase, glutamine synthase, Ara-70, Ara-54, human hypothetical proteins MGC 10526 or MGC 10233, FLJ20202, DCN-I protein, RAB5A, HSP-7C, EF1A1, GRP78, MYL4, DnaJ homolog subfamily B member 14, Vinculin, Desmoplakin, AMMECR1-like protein, Extracellular matrix protein 2 precursor protein, uncharacterised protein Cxorf57, Peroxiredoxin 1, and Peroxiredoxin 2.