Anti-idiotype antibody against an antibody against the amyloid beta peptide
AssigneeHoffmann-La Roche Inc.
InventorsULRICH ESSIG, WOLFGANG HOESEL, KAY-GUNNAR STUBENRAUCH, RUDOLF VOGEL
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Abstract
The present invention is directed to an anti-idiotype antibody binding to the complementary determining region of an antibody against the amyloid β peptide. In one embodiment said antibody binds to the same epitope or an overlapping epitope as the antibody obtainable from the cell line DSM ACC2939. Also reported is an immunoassay for the determination of an antibody against the amyloid β peptide and for determination of an anti-idiotype antibody binding to an antibody against the amyloid β peptide.
Claims11
An antibody that binds to a complementary determining region of an antibody against the amyloid β peptide and binds to the same epitope, or an overlapping epitope, as the antibody obtained from the cell line DSM ACC2939.
An antibody derived from the cell line DSM ACC2939.
A method for the immunological determination of an antibody against the amyloid β peptide in a sample comprising an immunoassay employing an antibody obtained from cell line DSM ACC2939.
A method for the immunological determination of an anti-idiotype antibody against an antibody against the amyloid β peptide in a sample comprising an immunoassay employing an antibody obtained from cell line DSM ACC2939.
Dependencies are inferred from the claim text.