Back to results
US 2010/0167282 A1Published application
Lateral-flow device and method to enhance detection signal for charged molecular targets
OwnerJui-Chuang Wu, Huan-Ching Yanginventors
Life of this patent
Estimating the term…
Abstract
The present invention proposes a lateral-flow device and method to enhance the detection signal for charged molecular targets. The device includes a detection assembly and a direct current source. The direct current is applied on the device to reduce the amount of residual target on the membrane and the detection limit is thus improved.
Claims22
A membrane based lateral-flow detection device for charged molecular targets, comprising:
- a membrane based lateral-flow detection assembly, said membrane based lateral-flow detection assembly comprising a sample pad, a conjugate pad, a membrane pad and an absorbent pad, and said membrane pad comprising a test line and a control line;
- and
- a direct current source, said direct current source comprising a first electrode and a second electrode, wherein the electricity of said first electrode is different from the electricity of said second electrode, said first electrode is located between said conjugate pad and said test line, and said second electrode is located between said control line and said absorbent pad, and wherein said charged molecular targets, with electricity different from the electricity of said second electrode, are forced to flow from said first electrode to said second electrode.
A membrane based lateral-flow detection method to enhance the detection signal for charged molecular targets, comprising:
- providing a plurality of charged molecular targets;
- providing a membrane based lateral-flow detection assembly, said membrane based lateral-flow detection assembly comprising a sample pad, a conjugate pad, a membrane pad and an absorbent pad, and said membrane pad comprising a test line and a control line;
- and
- providing a direct current source, said direct current source comprising a first electrode and a second electrode, wherein the electricity of said first electrode is different from the electricity of said second electrode, said first electrode is located between said conjugate pad and said test line, and said second electrode is located between said control line and said absorbent pad, and wherein said charged molecular targets, with electricity different from the electricity of said second electrode, are forced to flow from said first electrode to said second electrode.
1 more element
A membrane based lateral-flow detection device for charged molecular targets, comprising:
- a membrane based lateral-flow detection assembly, said membrane based lateral-flow detection assembly comprising a sample pad, a conjugate pad, a membrane pad and an absorbent pad, said membrane pad comprising a test line and a control line;
- and
- a direct current source connected to said membrane pad, said direct current source comprising a cathode and an anode, wherein said cathode is located between said conjugate pad and said test line, said anode is located between said control line and said absorbent pad, and said charged molecular targets are forced to flow from said cathode to said anode by an electromotive force provided by said direct current source.
Dependencies are inferred from the claim text.