Compositions, articles and methods for preventing or reducing tobacco-associated damage
AssigneeTechnion Research & Development Foundation Limited
InventorsMoshe Gavish, Rafael M. Nagler
Life of this patent
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Abstract
Articles of manufacturing, methods, devices and compositions for preventing or reducing tobacco-associated damage in a subject, and which utilize a metal ion chelating agent, a copper chelating agent, a penicillamine and/or a structural analog of penicillamine, with and without an additional antioxidant, are disclosed.
Claims54
An article of manufacturing comprising tobacco and a tobacco packaging material, wherein at least a portion of said tobacco and/or tobacco packaging material comprises an agent selected from the group consisting of penicillamine and a structural analog of penicillamine.
An article of manufacturing comprising tobacco and an agent being incorporated in at least a portion of said tobacco, said agent being selected from the group consisting of penicillamine and a structural analog of penicillamine.
An article of manufacturing comprising a tobacco packaging material and an agent being incorporated in at least a portion of said tobacco packaging material, said agent being selected from the group consisting of penicillamine and a structural analog of penicillamine.
A method of treating or preventing a tobacco-associated damage in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an agent selected from the group consisting of penicillamine and a structural analog thereof, thereby treating or preventing the tobacco-associated damage.
A pharmaceutical composition comprising an agent selected from the group consisting of penicillamine and a structural analog thereof and a pharmaceutically acceptable carrier, the composition being packaged in a packaging material and identified in print, in or on said packaging material, for use in the treatment of a tobacco-associated damage.
An article of manufacturing comprising a filter and an agent comprised with said filter, said agent being selected from the group consisting of penicillamine and a structural analog of penicillamine and said filter being designed and configured so as to enable release of said agent therefrom when in use by a subject.
An oral composition comprising an agent selected from the group consisting of penicillamine and a structural analog of penicillamine, the composition being in the form of a toothpaste, powder, liquid dentifrice, mouthwash, denture cleanser, chewing gum, lozenge, paste, gel or candy.
A medical device comprising an agent selected from the group consisting of penicillamine and a structural analog of penicillamine, the medical device being designed and configured to deliver said agent to a bodily site.
An article of manufacturing comprising tobacco and a tobacco packaging material, wherein at least a portion of said tobacco and/or tobacco packaging material comprises an agent, said agent being a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0.
An article of manufacturing comprising tobacco and an agent being incorporated in at least a portion of said tobacco, aid agent being a metal ion chelating agent, said metal being a redox active that can assume at least two oxidations states other than 0.
An article of manufacturing comprising a tobacco packaging material and an agent being incorporated in at least a portion of said tobacco packaging material, aid agent being a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0.
A method of treating or preventing a tobacco-associated damage in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an agent, aid agent being a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0.
A pharmaceutical composition comprising an agent and a pharmaceutically acceptable carrier, said agent being a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0, the composition being packaged in a packaging material and identified in print, in or on said packaging material, for use in the treatment of a tobacco-associated damage.
An article of manufacturing comprising a filter and an agent comprised with said filter, said agent being a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0 and said filter being designed and configured so as to enable release of said agent therefrom when in use by a subject.
An article of manufacturing comprising a filter and an agent comprised with said filter, said agent being a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0 and said filter being designed and configured so as to enable release of said agent therefrom when in use by a subject.
An oral composition comprising a metal ion chelating agent, said metal being a redox active metal that can assume at least two oxidations states other than 0, the composition being in the form of a toothpaste, powder, liquid dentifrice, mouthwash, denture cleanser, chewing gum, lozenge, paste, gel or candy.
A medical device comprising a metal ion chelating agent, said metal being a redox active that can assume at least two oxidations states other than 0, the medical device being designed and configured to deliver said agent to a bodily site.
Dependencies are inferred from the claim text.