Gras composition for intranasal delivery of parathyroid hormone
AssigneeMdrna, Inc.
InventorsHenry R. Costantino, Ching-Yuan Li
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Abstract
What is described is an aqueous pharmaceutical composition for intranasal delivery of PTH, comprising a PTH molecule, and one or more excipients selected from the group consisting of a chelating agent, an alcohol, and a surface active agent, wherein the PTH molecule selected from the group consisting of SEQ NO: 1, SEQ NO: 2, and SEQ NO: 3.
Claims15
A pharmaceutical composition for intranasal delivery comprising an aqueous solution of a PTH, a polyoxyethylene sorbitan ester, a polyol, and chlorobutanol, wherein the composition has greater than about 6% bioavailability of the PTH upon intranasal administration of the composition to a human.
Dependencies are inferred from the claim text.