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AssigneesJuridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kowa Company, Ltd.
InventorsToshihiro NAKASHIMA, Takumi Sasaki, Tsukasa Nishihara, Sumiyo Takemoto, Atsuko Sakata, Masao Ohkuchi, Tomoyuki Koshi, Toshiyuki Edano
Estimating the term…
A modified Staphylococcal enterotoxin B (SEB) having resistance to a protease and a reduced toxicity and a vaccine comprising said modified SEB are provided. A modified SEB which has an amino acid sequence as set forth in SEQ ID NO: 1 wherein each of the lysine at 97-position and the lysine at 98-position are substituted with any other amino acid, or a derivative thereof and a vaccine comprising said modified SEB or a derivative thereof.
A modified Staphylococcal enterotoxin B (SEB) having an amino acid substitution to allow for resistance to a protease, or a derivative thereof.
Dependencies are inferred from the claim text.