US 2010/0166672 A1 · FOAM-FORMING COMPOSITION

Abstract

The present invention relates to a novel foam-forming composition suitable for rectal administration of locally-acting pharmaceutically active ingredients, and the product adapted to administer said foam-forming composition. Also, the present invention relates to a method for its preparation. According to the present invention a foam-forming composition is provided which exhibits a high expansion ratio and at the same time conferring optimal appearance of the formed foam to allow sufficient contact time of the active to the target site in the intestine in order to obtain optimal local effect. The composition according to the present inventions provides superior properties for the treatment of rectal diseases.

Claims20

Dependent claims

An aqueous foam-forming composition for rectal administration of a therapeutically effective amount of prednisolone or its pharmaceutically acceptable derivatives, wherein said composition has a volume expansion ratio of at least 26.

Dependencies are inferred from the claim text.

Facts

Application

12/161,102Filed 12 Jan 2007

Priority

EP 06100572.419 Jan 2006

Published

1 Jul 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

A61K 9/0031
Galenical forms characterised by the site of application: rectum, anus
A61K 9/122
Aerosols; Foams: foams; Dry foams
A61K 31/573
Substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone: substituted in position 21, e.g. cortisone,…
A61K 47/26
Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite: carbohydrates, e.g. sugar alcohols,…

Foam-forming composition

Life of this patent

Foam-forming composition

Life of this patent

Abstract

Claims20