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US 2010/0145027 A1Published application
Compositions and Methods for the Diagnosis and Treatment of Tumor
AssigneeGenentech, Inc.
InventorsAvi J. Ashkenazi, Dan L. Eaton, Audrey Goddard, Austin L. Gurney, William I. Wood, Thomas D. Wu
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Abstract
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Claims10
An isolated polypeptide comprising an amino acid sequence having at least 95% amino acid sequence identity to:
- (a) the amino acid sequence of the polypeptide shown in FIG. 2 (SEQ ID NO:2),
- (b) the amino acid sequence of the polypeptide shown in FIG. 2 (SEQ ID NO:2), lacking its associated signal peptide,
- (c) the amino acid sequence of the full-length polypeptide encoded by the cDNA deposited under ATCC Accession No. 203127, or
- (d) the amino acid sequence of the full-length polypeptide encoded by the cDNA deposited under ATCC Accession No. 203127, lacking its associated signal peptide;
- wherein said isolated polypeptide can be used to generate an antibody which can be used to specifically detect the polypeptide of SEQ ID NO:2 in breast tissue samples.
2 more elements
Dependencies are inferred from the claim text.