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US 2010/0144860 A1Published application
Transglutaminase Inhibitor Comprising EGCG And A Method For Producing Thereof
OwnerSoo Youl Kim, Kyung Chae Jeonginventors
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OwnerSoo Youl Kim, Kyung Chae Jeonginventors
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The present invention relates to a transglutaminase inhibitor comprising epigallocatechin gallate (hereinafter, referred to as EGCG). More particularly, the present invention relates to a transglutaminase inhibitor comprising EGCG which effectively inhibits the activity of transglutaminase, the overexpression of which is responsible for the etiology of various diseases, and to novel uses thereof. According to the present invention, provided is a transglutaminase inhibitor and a method of inhibiting transglutaminase, featuring the use of EGCG as an active ingredient. Featuring the use of EGCG, the novel method of inhibiting transglutaminase according to the present invention is safely applied to patients who suffer from the diseases caused by the overexpression of transglutaminase, thereby obtaining an inhibitory effect against transglutaminase without casuing side-effects.
A transglutaminase inhibitor, comprising epigallocatechin gallate (EGCG) or a derivative thereof.
A method of inhibiting an activity of transglutaminase using EGCG or a derivative thereof.
A pharmaceutical composition for the treatment or prevention of a disease caused by the activation of transglutaminase, comprising EGCG or a derivative thereof.
Dependencies are inferred from the claim text.