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US 2010/0144828 A1Published application
Caffeoylquinic acid derivatives containing nitrogen, and preparation method, pharmaceutical composition and usage thereof
AssigneeZhejiang Medicine Co., Ltd. Xinchang Pharmaceutica
InventorsZhanggui Wu, Wei Wei
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Abstract
The present invention provides caffeoylquinic acid derivatives and a method of preparing for the same, and also provides pharmaceutical compositions containing caffeoylquinic acid derivatives, and uses of caffeoylquinic acid derivatives in preparation of a medicament for the treatment or prophylaxis of virus diseases, in particular, uses of respiratory syncytial virus and hepatitis B virus, which has the characteristics of safety, high effectiveness and low toxicity.
Claims20
A compound having Formula (1) or salts or hydrates thereof,
- wherein R represents NH2, or any mono-substituted or di-substituted C1-C6 alkylamino group with straight chain or branched chain, or any substituted C3-C6 naphthenic amino group, or any substituted C1-C6 aromatic amino group, or pyrrolidinyl group or piperidyl group;
- Q1, Q2, Q3, Q4 represent H or the following Formula (II) or a combination thereof, wherein Q1, Q2, Q3, Q4 cannot all represent H at the same time and Q1, Q2, Q3, Q4 cannot all represent Formula (II) at the same time.
Dependencies are inferred from the claim text.