Oleyl phosphocholine
AssigneeMax-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
InventorHansjörg Eibl
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Abstract
The invention relates to the use of oleyl phosphocholine and oleyl-phospho-(N.N.-dimethyl-N-ethyl)-ethyl-ammonium for the long-term and continuous treatment of serious illnesses, such as cancer, leishmaniasis, ehrlichiosis, multiple sclerosis and psoriasis, in addition to other indications mentioned in the application.
Claims8
The use of the compounds of the formula (I)
- R1—O—PO2(−)—O—(CH2)2—N(+)—R2(CH3)2 (I)
- wherein
- R1 is an oleyl residue and
- R2 means CH3,
- for the production of a drug for the treatment of protozoan diseases, in particular leishmaniasis, sleeping sickness, amoebic dysentery or encephalitis, bacterial diseases, in particular ehrlichiosis, cancer, in particular leukemia, solid tumors, Cushin's disease or bladder tumors, multiple sclerosis, acariosis, eye diseases, fungal diseases and/or psoriasis, in which the drug is intended for administration in a quantity of 0.1 to 0.9 mg/kg body weight/day.
A method for the treatment of protozoan diseases, bacterial diseases, cancer, multiple sclerosis, acariosis, eye diseases, fungal diseases and/or psoriasis, in a patient in need of such treatment, comprising administering to the patient a compound of the formula (I)
- R1—O—PO2(−)—O—(CH2)2—N(+)—R2(CH3)2 (I)
- wherein
- R1 is an oleyl residue and
- R2 means CH3,
- in an amount of of 0.1 to 0.9 mg/kg body weight/day.
Dependencies are inferred from the claim text.