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AssigneesYM Biosciences Inc., University of Manitoba
InventorsMark VINCENT, Lorn J. Brandes
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The present invention provides for the use of N,N-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine monohydrochloride (DPPE) in cancer therapy. DPPE is used in the treatment of patients having, or suspected of having, an aggressive cancer. The present invention further provides for the use of DPPE in the treatment of a patient suspected of having an existing cancer, wherein the use follows a surgery for treatment of a primary cancer that is estrogen-receptor negative. Also provided are pharmaceutical compositions comprising DPPE for use in the treatment of patients having, or suspected of having, an aggressive cancer and pharmaceutical kits comprising such compositions.
A method of treating a cancer patient selected as a patient having an aggressive breast cancer, which comprises administering N,N-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine monohydrochloride (DPPE) to the patient to thereby extend the survival of said patient wherein the aggressive cancer is such that the patient requires chemotherapy for advanced disease in 40 months or less following a diagnosis of a primary cancer and is estrogen receptor negative.
A method of extending the survival of a patient having aggressive breast cancer, comprising
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