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US 2010/0143492 A1Published application
Coagulation and fibrinolytic cascades modulator
AssigneeThe Board of Trustees of the University of Illinios
InventorsJAMES H. MORRISSEY, STEPHANIE A. SMITH, ROBERTO DOCAMPO, NICOLA J. MUTCH
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Abstract
A thromboplastin reagent comprises (i) TF, (ii) a phospholipid, and (iii) a polyP TFPI blocker.
Claims24
1-8. (canceled)
A composition for promoting clotting, comprising:
- (i) polyP, and
- (ii) a pharmaceutical carrier.
(canceled)
A method of stopping or slowing bleeding from a wound, comprising contacting blood from the wound with polyP.
A method of slowing fibrinolysis, comprising contacting fibrin with polyPn, where n greater than 25.
A method of blocking TFPI, comprising including polyP in a composition comprising the TFPI.
31-35. (canceled)
Dependencies are inferred from the claim text.