US 2010/0143487 A1 · BIOCOMPATIBLE PROTEIN-BASED PARTICLES AND METHODS THEREOF

Abstract

The present invention relates to biocompatible protein-based particles and their methods of preparation and use. More specifically the present invention relates protein-based particles including protein matrix, spread matrix and/or biocoacervate materials derived from one or more biocompatible purified proteins combined with one or more biocompatible solvents that are used to replace or repair tissue and/or bone in treatments for spinal disc(s), joint(s) (e.g. knee, hip, finger, ankle, elbow, shoulder . . . ) and organ(s) (e.g. bladder, lips, vagina, penis, urethra . . . ). In various embodiments of the present invention the protein-based particles may also include one or more pharmacologically active agents and/or one or more additives.

Claims30

Dependent claims

A method of treating or enhancing the function of a spinal disc comprising:

administering a plurality of particles to the spinal disc or the surrounding fluid, space, tissue or bone of the spinal disc, said particles comprising one or more protein-based biomaterials at least partially produced from one or more biocoacervate material(s), the biocoacervate material(s) precipitated from a solution including one or more biocompatible protein(s), one or more glycosaminioglycans and one or more biocompatible solvents.

Dependencies are inferred from the claim text.

Facts

Application

12/344,361Filed 26 Dec 2008

Priority

26 Dec 2007

Published

10 Jun 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification5 codes

A61K 9/0019
Galenical forms characterised by the site of application: injectable compositions; Intramuscular, intravenous, arterial, subcutaneous…
A61K 9/14
Medicinal preparations characterised by special physical form: particulate form, e.g. powders, Processes for size reducing of pure drugs or the…
A61P 19/08
Drugs for skeletal disorders: for bone diseases, e.g. rachitism, Paget's disease
A61K
Medicines and medical preparations

Biocompatible protein-based particles and methods thereof

Life of this patent

Biocompatible protein-based particles and methods thereof

Life of this patent

Abstract

Claims30