Hybrid Biomimetic Particles, Methods of Making Same and Uses Therefor
AssigneeThe University of Toledo
InventorsA. Champa Jayasuriya, Nabil A. Ebraheim
Life of this patent
Estimating the term…
Abstract
Biomimetic microparticles for generation of tissue includes a biodegradable tissue replacement/repair matrix formed of a cross-linked scaffold material using a non-toxic multi-valent ionic cross-linking agent. One or more bioactive materials can be encapsulated and/or coated onto the biodegradable tissue replacement/repair matrix. The biomimetic microparticles are formed without exposure to high temperatures, high pressures, high voltages, and toxic chemicals.
Claims84
A biomimetic microparticle comprising
- one or more scaffold materials at least partially crosslinked with one or more non-toxic cross-linking agents to form a biodegradable tissue replacement/repair matrix, and
- one or more reinforcement materials at least partially incorporated into the biodegradable tissue replacement/repair matrix.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
The method of clam 72, wherein step (b) is carried out by injection.
The method of clam 73, wherein the injection is substantially directly into the tissue.
The method of clam 72, wherein the injection is at a tissue site in need of tissue generation.
(canceled)
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.