Polypeptides for inducing a protective immune response against staphylococcus epidermidis

An immunogen comprising an amino acid sequence at least 85% identical to SEQ ID NO:

• 1 and one or more additional regions or moieties covalently joined to said amino acid sequence at the carboxyl terminus or amino terminus, wherein each region or moiety is independently selected from a region or moiety having at least one of the following properties:
• enhances the immune response, facilitates purification, or facilitates polypeptide stability.

A method of inducing a protective immune response in a patient comprising the step of administering to said patient an immunologically effective amount of immunogen comprising an amino acid sequence at least 85% identical to SEQ ID NO:

• 1.