Antitumor agent
AssigneeZeria Pharmaceutical Co., Ltd.
InventorsKoji YOSHINAGA, Daisuke Kawasaki, Yutaka Emori
Life of this patent
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Abstract
To provide a pharmaceutical agent or an antitumor agent useful for the treatment and/or prevention of gastrointestinal cancer, leukemia, pituitary tumor, small cell lung cancer, thyroid cancer, and neuroastrocytoma. The antitumor agent containing, as an active ingredient, a 1,5-benzodiazepine derivative represented by the following formula (1): (wherein R1 represents a C1-6 alkyl group; R2 represents a phenyl group or a cyclohexyl group; and Y represents a single bond or a C1-4 alkylene group) or a pharmaceutically acceptable salt thereof.
Claims10
A multi-drug anti-gastrointestinal tumor composition comprising, as ingredients, a 1,5-benzodiazepine represented by the following formula (1):
- wherein R1 represents a C1-6 alkyl group;
- R2 represents a phenyl group or a cyclohexyl group;
- and Y represents a single bond or a C1-4 alkylene group or a pharmaceutically acceptable salt thereof;
- and (B) an antitumor agent.
7-8. (canceled)
10-27. (canceled)
A multi-drug anti-pancreatic tumor composition comprising, as ingredients, a 1,5-benzodiazepine represented by the following formula (1):
- wherein R1 represents a C1-6 alkyl group;
- R2 represents a phenyl group or a cyclohexyl group;
- and Y represents a single bond or a C1-4 alkylene group or a pharmaceutically acceptable salt thereof;
- and (B) an antitumor agent.
Dependencies are inferred from the claim text.