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US 2010/0143309 A1Published application
Viral vectors
AssigneeBiovex Limited
InventorsRobert Stuart Coffin, Guy Richard Simpson
Life of this patent
Estimating the term…
Abstract
The present invention provides a herpes virus which lacks a functional ICP34.5 encoding gene and which comprises two or more of—(i) a gene encoding a prodrug converting enzyme; (ii) a gene encoding a protein capable of causing cell to cell fusion; and (iii) a gene encoding an immunomodulatory protein.
Claims16
1-20. (canceled)
A herpes virus which lacks a functional ICP34.5 encoding gene and which comprises:
- (i) a heterologous gene encoding a prodrug converting enzyme;
- and
- (ii) a heterologous gene encoding a protein capable of causing cell
- to cell fusion.
1 more element
A pharmaceutical composition comprising as active ingredient a virus according to claim 1 and a pharmaceutically acceptable carrier or diluent.
Dependencies are inferred from the claim text.