Use of the augmenter of liver regeneration protein as an apoptosis regulator
OwnerLorenzo Polimeno, Antonio Francavillainventors
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Abstract
The invention relates to a new use of the protein called Augmenter of Liver Regeneration (Alrp) in the regulation and control of apoptosis in mammals.
Claims15
The use of the Augmenter of Liver Regeneration (Alrp) as a regulator of apoptosis.
A pharmaceutical or veterinary composition comprising Alrp as the active ingredient.
The use of Alrp as a marker for detecting the presence of a proliferative disease.
The use of antibodies anti-Alrp for the preparation of a medicament for the treatment of a disease wherein a down-regulation of apoptosis is beneficial.
The use of antibodies anti-Alrp for the preparation of a diagnostic agent.
The use of Alrp for the preparation of cell lines.
The use of Alrp encoding sequence for the preparation of immortal cell lines.
The use of a transgenic non-human mammal transformed with an ALR gene sequence for experimental tests on apoptosis.
Dependencies are inferred from the claim text.