Polymer factor ix moiety conjugates
AssigneeNektar Therapeutics
InventorsMary J. Bossard, Gayle Stephenson
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Abstract
Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
Claims30
A composition that is substantially free from albumin comprising a conjugate comprising a Factor IX moiety covalently attached, either directly or through a spacer moiety comprised of one or more atoms, to at least one but not more than three water-soluble polymers.
Dependencies are inferred from the claim text.