Tnik inhibitor and the use

A compound represented by the following general formula:

• (wherein R1′ and R2′ independently represent a hydrogen atom, a halogen atom, a hydroxy group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted amino group, an acylamino group, a nitro group, a substituted or unsubstituted alkoxycarbonylamino group, R3′ and R4′ independently represent a hydrogen atom, a halogen atom, a hydroxy group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted amino group, a substituted or unsubstituted acylamino group or a substituted or unsubstituted alkyl sulfonamido group, and Y1, Y2 and Y3 independently represent a nitrogen atom or a carbon atom.), or a pharmaceutically acceptable salt thereof.