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US 2010/0137215 A1Published application
Novel tetrahydro-1h-pyrido[4,3-b]indoles
AssigneeConcert Pharmaceuticals, Inc.
InventorsI. Robert Silverman, Craig E. Masse
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Abstract
This invention relates to novel tetrahydro-1H-pyrido[4,3-b]indoles, their derivatives and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by NMDA antagonists, acetylcholinesterase inhibitors, 5-HT6 antagonists, other neuroprotectors, antihistamines and agents that delay age-related pathologies and conditions.
Claims17
A compound of the formula:
- or a pharmaceutically acceptable salt thereof, wherein:
- each R is independently selected from CH3, CD2H, CDH2 and CD3;
- each X is independently selected from H and D;
- each Y is independently selected from H and D;
- each Z is independently selected from H and D;
- and
- when each R is CH3, at least one X, Y or Z is D.
4 more elements
Dependencies are inferred from the claim text.