Cell Culture Tube and Multiple Roller Tube Cell Culture Apparatus Including the Same

A multiple roller tube cell culture apparatus, comprising:

• a cylindrical housing 14 for accommodating at least one drum 13 with a bundle of cell culture tubes 18 arranged therein, rotatable around a shaft 21 of the housing, said cell culture tubes 18 having two elliptical or semi-elliptical openings 19 formed in respective end walls thereof;
• a driving means 20 for rotating the drum 13;
• a medium reservoir 30 for storing a fresh culture medium to be fed into the drum 13;
• and
• a harvest reservoir 40 for storing a culture product grown in the drum 13, wherein each of the cell culture tubes 18a, having two elliptical openings 19a at respective end walls thereof, is positioned near the shaft 21, and each of the cell culture tubes 18b, having two semi-elliptical openings 19b in respective end walls thereof, is arranged at a position distant from the shaft and near an inner circumference of the drum 13.