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US 2010/0136213 A1Published application
Thermal Treatment of a Drug Eluting Implantable Medical Device
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsSyed F.A. Hossainy, Fuh-Wei Tang, Stephen D. Pacetti, Jeff Royal, Dorrie M. Happ, Kurt Scheinpflug, Ty Hu
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Abstract
A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.
Claims17
A method of manufacturing a drug delivery stent, comprising:
- forming a dry polymeric coating on a stent having less than about 2% residual fluid content (w/w), the dry polymeric coating comprising a reservoir layer including a polymer and an active agent, and a barrier layer including a polymer covering a portion of the reservoir layer;
- and
- subjected the polymer included in the barrier layer to a heat treatment at a temperature equal to or greater than the glass transition of the polymer.
A method of manufacturing a drug delivery stent, comprising:
- forming a polymeric coating on a stent, the polymeric coating comprising a reservoir layer including a polymer and an active agent, and a barrier layer including a semicrystalline polymer covering a portion of the reservoir layer;
- and
- exposing the polymer included in the barrier layer to the crystallization temperature of the polymer.
Dependencies are inferred from the claim text.