System for determining a distribution of radioactive agents in a subject

A system (400) for determining a biodistribution (404) of radioactive agents in a subject (409), comprising:

• a detector system (401) comprising two or more detectors (310a-310f) having at least one measuring rate and arranged to be attached to the subject (409) at localized areas for measuring radiation emitted from the radioactive agents at localized tissues (300-305) within the subject, the localized tissues including at least one target tissue, the measured radiation resulting in separate radiation data sets being associated to the localized tissues, the detectors (310a-3100 further being arranged to adapt the measuring rate to pharmacokinetic behavior of the localized tissues (300-305), and
• a processor (402) for processing the separate radiation data sets for determining radioactivity within each respective localized tissue from the localized tissues (300-305) and based thereon, biodistribution of the radioactive agents within the subject (409).