Low radiocarbon dietary supplements and methods of making same

A method for reducing the radiocarbon content of genetic material in a vertebrate, said genetic material including DNA and histones, comprising providing to said vertebrate at least one low-radiocarbon dietary supplement comprising at least one member, including enantiomers, stereoisomers, rotamers, tautomers, racemates and nutritionally acceptable salts or solvates thereof, selected from the group consisting of:

• (A) a DNA precursor selected from the group consisting of purines, pyrimidines, ribose, deoxyribose, nucleosides, deoxynucleosides, nucleotides, deoxynucleotides, and derivatives and mixtures thereof;
• (B) a histone precursor selected from the group consisting of amino acids and derivatives and mixtures thereof, wherein at least about 50% of the low radiocarbon amino acid carbon atoms are contributed by Lys and at least one amino acid selected from the group consisting of Arg, Leu, Ala, Val, Ile, Thr, Glu, Tyr, Pro, Ser, Gly, and Gln;
• and (C) mixtures of (A) and (B);
• said low-radiocarbon dietary supplement exhibiting a level of radiocarbon that is at least about 50% lower than the natural radiocarbon abundance level.

A method for reducing the radiocarbon content of genetic material in a vertebrate, said genetic material including DNA and histones, comprising providing to said vertebrate at least one low-radiocarbon dietary supplement comprising at least one member, including enantiomers, stereoisomers, rotamers, tautomers, racemates and nutritionally acceptable salts or solvates thereof, selected from the group consisting of:

• (A) a DNA precursor selected from the group consisting of purines, pyrimidines, ribose, deoxyribose, nucleosides, deoxynucleosides, nucleotides, deoxynucleotides, and derivatives and mixtures thereof;
• (B) a histone precursor selected from the group consisting of amino acids and derivatives and mixtures thereof;
• and
• (C) mixtures of (A) and (B);
• said low-radiocarbon dietary supplement exhibiting a level of radiocarbon that is at least about 50% lower than the natural radiocarbon abundance level;
• said method further comprising:
• (D) providing for ingestion by said vertebrate foods comprising:
• (1) natural background level of radiocarbon;
• and (2) lower than average levels of components selected from the group consisting of proteins, nucleotides, DNA precursors, amino acids, and mixtures thereof;
• preferably said foods selected from the group consisting of fruits, including cherries, strawberries, blueberries, and other red-blue berries, and bananas;
• vegetables, including celery, tomatoes, kale, cabbage, parsley, and green-leafy vegetables;
• foods high in bromelain, including pineapple;
• foods high in vitamin C, including red cabbage, red bell peppers, tangerines, mandarins, oranges, and potatoes;
• fruit juices;
• complex carbohydrates, including breads, cereals, pasta, rice, vegetables, and fruits;
• and mixtures thereof;
• and
• (E) avoiding providing for ingestion by said vertebrate foods comprising:
• (1) natural background level of radiocarbon;
• and (2) higher than average levels of components selected from the group consisting of proteins, nucleotides, DNA precursors, amino acids, and mixtures thereof;
• preferably said foods selected from the group consisting of meats, beans and mixtures thereof.