Microorganism Producing Inosine and Method of Producing Inosine Using the Same
AssigneeCj Cheiljedang Corporation
InventorsYoung-hoon Park, Kwang-myung Cho, Hee-jong Lee, Jin-nam Lee
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AssigneeCj Cheiljedang Corporation
InventorsYoung-hoon Park, Kwang-myung Cho, Hee-jong Lee, Jin-nam Lee
Estimating the term…
The present invention relates to a microorganism producing inosine, which is one of purine nucleoside, an important material for 5′-inosinic acid synthesis, and method for producing inosine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebacterium genus producing inosine at high concentration by inactivating the gene encoding nucleoside hydrolase II and by enhancing the expression of the gene encoding 5′-nucleotidase, which still retains the characteristics of Corynebacterium ammoniagenes CJIP2401 (KCCM-10610).
A Corynebacterium ammoniagenes producing inosinic acid and inosine by inactivating the gene encoding nucleoside hydrolase II having the nucleotide sequence represented by SEQ. ID. NO:
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