Rotary array module for multiplexing spot-based optical readouts

An apparatus for detecting a target molecule in a liquid sample, comprising:

• a sample chamber adapted to hold a liquid sample and including an interrogation region;
• a rotary array disposed in said sample chamber and rotatable about an axis of rotation in the liquid sample, said rotary array including an annular portion radially spaced from said axis of rotation in radial alignment with said interrogation region and a plurality of spots disposed at angularly spaced locations on said annular portion, each spot including at least one probe molecule selected to bind to a particular region of a target molecule;
• and
• an optical detection system configured to illuminate each spot via said interrogation region as the array rotates in a liquid sample within said sample chamber and to monitor emissions from said spot to determine if a target molecule has bound to one of said probe molecules.