Human anti-amyloid antibodies, compositions, methods and uses

At least one isolated human amyloid antibody, comprising either (i) at least two of the heavy chain complementarity determining regions (CDR) amino acid sequences of at least one of SEQ ID NOS:42-44;

• or (ii) at least two of the light chain CDR amino acids sequences of at least one of SEQ ID NOS:45-47, and further comprising at least one human heavy chain or light chain constant region fragment selected from CH1, CH2, CH3 or CH4.

At least one isolated human amyloid antibody, comprising at least one heavy chain or light chain CDR having the amino acid sequence of at least one of SEQ ID NOS:48-56 and SEQ ID NOS:57-69.

At least one isolated human amyloid antibody that binds to the same region of an amyloid polypeptide as an antibody comprising at least one heavy chain or light chain CDR having the amino acid sequence of at least one of SEQ ID NOS:42-47, and further comprising at least one human heavy chain or light chain constant region fragment selected from CH1, CH2, CH3 or CH4.

At least one isolated human amyloid antibody, comprising at least one variable region comprising at least one heavy chain and at least one light chain of SEQ ID NOS:56 and 69, and further comprising at least one human heavy chain or light chain constant region fragment selected from CH1, CH2, CH3 or CH4.

An isolated nucleic acid encoding at least one isolated human amyloid antibody according to any of claims 1-10.

Any invention described herein.