Composition containing human umbilical cord blood-derived mesenchymal stem cell for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells
AssigneeMedipost Co., Ltd.
InventorsWonil Oh, Yoon-Sun Yang, Jong Wook Chang, Soo Jin Choi, Ju-Yeon Kim
Life of this patent
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Abstract
A use of a composition comprising umbilical cord blood-derived mesenchymal stem cells for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells is provided, the composition being effective for the treatment of nerve injury diseases.
Claims19
1-7. (canceled)
A method for proliferating neural precursor cells or neural stem cells which comprises bringing the neural precursor cells or neural stem cells to be in contact with umbilical cord blood-derived mesenchymal stem cells.
A method for differentiating neural precursor cells or neural stem cells into neural cells, which comprises bringing the neural precursor cells or neural stem cells to be in contact with umbilical cord blood-derived mesenchymal stem cells, optionally together with an agent which is capable of differentiating the neural precursor cells or neural stem cells into neural cells.
A method for simultaneously proliferating neural precursor cells or neural stem cells and differentiating the neural precursor cells or the neural stem cells into neural cells, which comprises bringing the neural precursor cells or neural stem cells to be in contact with umbilical cord blood-derived mesenchymal stem cells, optionally together with an agent which is capable of differentiating the neural precursor cells or neural stem cells into neural cells.
A method for treating a nerve injury disease, which comprises administering umbilical cord blood-derived mesenchymal stem cells to a nerve cell injury region of a subject in need of treating the nerve injury disease.
Dependencies are inferred from the claim text.