Systems and methods for freezing, storing and thawing biopharmaceutical materials

A system for use in storing biopharmaceutical materials, said system comprising:

• a container for holding biopharmaceutical materials therein,
• a sensor coupled to said container for monitoring a physical parameter of the biopharmaceutical materials in the container;
• a holder having a storage cavity receiving said container and a sampling cavity receiving said sensor;
• said holder comprising a first portion and a second portion, said container received between said first portion and said second portion to connect said container to said holder;
• said holder comprising an interior storage cradle bounding said storage cavity;
• said holder comprising an interior sampling cradle bounding said sampling cavity, said sampling cradle separated from said storage cradle and connected to said storage cradle by a passage of said holder;
• and
• said holder comprising an outer rim connected to said storage cradle and separated from said storage cavity.

A method for use in storing biopharmaceutical materials, the method comprising:

• receiving a container holding biopharmaceutical materials in a holder having a storage cavity and a sampling cavity;
• connecting the container to the holder by receiving the container between a first portion and a second portion of the holder;
• an interior storage cradle of the holder bounding the storage cavity;
• an interior sampling cradle of the holder bounding the sampling cavity, the sampling cavity separated from the storage cavity, and the sampling cavity connected to the storage cavity by a connecting passage of the holder;
• and
• an outer rim of the holder connecting to the storage cradle and separated from the storage cavity.

A system for use in freezing, storing and thawing biopharmaceutical materials, said system comprising:

• a container for holding biopharmaceutical materials therein, said container comprising a storage portion and a sampling portion connected to each other by a connecting portion;
• a holder having a storage cavity receiving said storage portion and a sampling cavity receiving said sampling portion;
• said holder comprising a first portion and a second portion, said container received between said first portion and said second portion to connect said container to said holder;
• said holder comprising an interior storage cradle bounding said storage cavity;
• said holder comprising an interior sampling cradle bounding said sampling cavity, said sampling cradle separated from said storage cradle and connected to said storage cradle by a passage receiving the connecting portion connecting said storage portion to said sampling portion;
• said sampling portion separated from said storage portion at a sealed portion between said sampling portion and said storage portion;
• and
• said holder comprising an outer rim connected to said storage cradle and separated from said storage cavity.