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US 2010/0063105 A1Published application
Pharmaceutical uses and synthesis of nicotinanilide-n-oxides
AssigneeUcb, S.A.
InventorsNeil S. Cutshall, Kraig M. Yager
Life of this patent
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Abstract
Disclosed are nicotinanilide-N-oxide compounds, methods for their production, pharmaceutical compositions which include these compounds, and methods for their use in various therapies.
Claims20
A compound having the structure (I):
- and optical isomers, diastereomers, enantiomers and pharmaceutically acceptable salts thereof, wherein
- R1 is halide or (C1-C6alkyl)S;
- R2 is hydrogen;
- R3 is phenyl;
- and
- each occurrence of R4 is independently selected from halogen, and alkyl;
- and
- n is 0, 1, or 2.
5 more elements
4-10. (canceled)
12-29. (canceled)
34-35. (canceled)
39-40. (canceled)
(canceled)
A compound having the formula 2-chloro-5-(2,4-difluorobenzylcarbamoyl)pyridine 1-oxide.
Dependencies are inferred from the claim text.