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US 2010/0062977 A1Published application
TCR-Independent Activation of T Cells
AssigneeNovartis Vaccines and Diagnostics, Inc.
InventorsAlessandro Serra, Andreas Wack
Life of this patent
Estimating the term…
Abstract
A method for TCR-independent T cell activation which comprises the co-ligation of CD28 and CD81.
Claims39
A method for TCR-independent T cell activation which comprises the co-ligation of CD28 and CD81.
22-24. (canceled)
A pharmaceutical composition which comprises a CD28 ligand.
29-53. (canceled)
A method of upregulating the immune system of an individual wherein said method comprises administering a CD28 ligand to the individual.
A kit comprising a CD28 ligand and a CD81 ligand.
An ex vivo method for switching type 1 T cells to type 2 T cells which comprises the ligation of CD28 with a superagonist.
Dependencies are inferred from the claim text.